Pot May Halt MRSA

Yet Another Study Reports That Pot May Halt MRSA
Tue, 09 Sep 2008 21:42:58 By: Paul Armentano, NORML Deputy Director

Just days after the New York Times, Scientific American, and other MSM outlets finally got wind that cannabis’ germ-fighting properties can halt the spread of MRSA and other multi-drug resistant pathogens, along comes a second just-released study identifying several new non-cannabinoid compounds in the plant which possess anti-bacterial properties.

Investigators at the University of Mississippi report the discovery of eleven new non-cannabinoid constituents in cannabis, several of which possess “anti-microbial” (think MRSA), “anti-malarial,” and “anti-leishmanial” (a common skin parasite) activity. Scientists also reported that several of the compounds also possessed anti-inflammatory properties and acted as potent anti-oxidants.

(The US government, Depart of Health and Human Services actually holds a patent on the use of certain cannabinoids as anti-oxidants and neuroprotectants, which you can read here.)

In other words, when we speak about the healing powers of the cannabis plant, we really mean the entire cannabis plant. We’re not talking about isolating particular cannabinoids, and we’re most certainly not suggesting patients be forced to consume an oral synthetic version of a single compound a la Marinol.

Therapeutic cannabis means just that — the therapeutic prowess of the whole plant. We should not advocate for, or accept, anything less.

National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, MS 38677, USA.

Six new non-cannabinoid constituents were isolated from a high potency Cannabis sativa L. variety, namely 5-acetoxy-6-geranyl-3-n-pentyl-1,4-benzoquinone (1), 4,5-dihydroxy-2,3,6-trimethoxy-9,10-dihydrophenanthrene (2), 4-hydroxy-2,3,6,7-tetramethoxy-9,10-dihydrophenanthrene (3), 4,7-dimethoxy-1,2,5-trihydroxyphenanthrene (4), cannflavin C (5) and beta-sitosteryl-3-O-beta-d-glucopyranoside-2'-O-palmitate (6). In addition, five known compounds, alpha-cannabispiranol (7), chrysoeriol (8), 6-prenylapigenin (9), cannflavin A (10) and beta-acetyl cannabispiranol (11) were identified, with 8 and 9 being reported for the first time from cannabis. Some isolates displayed weak to strong antimicrobial, antileishmanial, antimalarial and anti-oxidant activities. Compounds 2-4 were inactive as analgesics.

PMID: 18774146 [PubMed - as supplied by publisher]

Related Articles

* Isolation and characterization of new Cannabis constituents from a high potency variety. [Planta Med. 2008]